中国真菌学杂志2013，Vol.8Issue(3)：163-168,6.
中国大陆地区接合菌病流行现状的回顾性分析
Epidemiology of zygomycosis in mainland China
王思卜 1李若瑜 1余进1
作者信息
- 1. 北京大学第一医院皮肤科,北京大学真菌与真菌病研究中心,北京100034
- 折叠
摘要
Abstract
Objective To understand the epidemiology of zygomycosis and the status of diagnosis and treatment in mainland China.Methods Literature from 1976 to 2010 were collected by CNKI and Pubmed and statistically analyzed.Results A total of 206 cases and 428 patients were included in our study.The most common infections of gastrointestinal,pulmonary,sinus and cutaneous sites were often secondary to diabetes,gastrointestinal ulceration,burns,surgery,trauma,or no underlying conditions.Etiology diagnosis depended on direct microscopy,culture and pathology,and only 6 cases identified by molecular biology.The antifungal therapy was the main treatment and amphotericin B was the first choice in most cases.The mortality was 29.43％ (126/428).Conclusions Zygomycosis in mailand China had emerged as an increasingly important fungal infection which was in concordance with the world.Gastrointestinal tract was the most popular involvement.Morphological and molecular biological identification are important for accurate and prompt diagnosis.In vitro susceptibility test is helpful for clinical treatment.关键词
接合菌病/菌种鉴定/诊断/治疗Key words
zygomycosis / species identification/diagnosis/treatment分类
医药卫生引用本文复制引用
王思卜,李若瑜,余进..中国大陆地区接合菌病流行现状的回顾性分析[J].中国真菌学杂志,2013,8(3):163-168,6.
