中国当代儿科杂志2013，Vol.15Issue(8)：671-677,7.DOI:10.7499/j.issn.1008-8830.2013.08.016
儿茶酚胺敏感性多形性室性心动过速患者的长期预后及室性心律失常的预测
Long-term outcomes and factors for predicting ventricular arrhythmia in patients with catecholaminergic polymorphic ventricular tachycardia
于圣永 1沈建华 2陆敬平 1赵东生 1张刚 1耿洁 1单其俊1
作者信息
- 1. 南京医科大学第一附属医院心血管科,江苏南京210029
- 2. 苏北人民医院心血管科,江苏扬州 225001
- 折叠
摘要
Abstract
Objective To evaluate factors for predicting ventricular arrhythmia,the clinical effect of drugs on patients with catecholaminergic polymorphic ventricular tachycardia (CPVT),and their long-term outcomes.Methods Six patients diagnosed with CPVT underwent a series of electrocardiograms and 24-hour Holter monitoring.β-bloekers were recommended for all patients,while some patients were also prescribed propafenone and 1 patient underwent catheter-based renal sympathetic denervation (RDN).The characteristics of electrocardiogram,arrhythmia and long-term outcomes were monitored.Results Syncope episodes did not occur any longer in 1 patient on β-blocker,but recurred in 3 other patients and 2 patients died (one due to his cessation of metoprolol for 3 months).Inverted and/or bifid T waves and abnormal U wave were observed in the precordial leads.T wave altemans was observed in 4 patients in the precordial leads.These abnormal electrocardiogram features disappeared or diminished with β-blocker treatment.All spontaneous episodes of ventricular tachycardia occurred prior to sinus tachycardia and frequent polymorphic premature ventricular contractions.Conclusions Bifid and/or inverted T waves,T wave alternans and abnormal U waves together with sinus tachycardia and frequent premature ventricular contractions are indicator for predicting ventricular arrhythmia and assessing the effect of β-blockers.Compliance with β-blocker treatment is a strong indicator of outcome.关键词
儿茶酚胺敏感性多形性室性心动过速/β受体阻滞剂/猝死/儿童Key words
Catecholaminergic polymorphic ventricular tachycardia/ β-blocker/ Sudden death/ Child引用本文复制引用
于圣永,沈建华,陆敬平,赵东生,张刚,耿洁,单其俊..儿茶酚胺敏感性多形性室性心动过速患者的长期预后及室性心律失常的预测[J].中国当代儿科杂志,2013,15(8):671-677,7.
