中国药房2013，Vol.24Issue(30)：2854-2856,3.DOI:10.6039/j.issn.1001-0408.2013.30.25
191例药物致过敏性休克不良反应文献分析
Literature Analysis of 191 Cases of Drug-induced Allergic Shock
摘要
Abstract
OBJECTIVE:To investigate the rules and characteristics of drug-induced allergic shock,and to provide reference for rational use of drugs in the clinic and the prevention of severe adverse drug reaction.METHODS:Using allergic shock and adverse drug reaction as key words,case reports of drug-induced allergic shock were retrieved from CNKI during 2001-2011,and then included cases were analyzed statistically.RESULTS:Top 3 drugs in the list of the incidence of allergic shock were antimicrobials,TCM preparation and digestive system drugs; and allergic shock induced by intravenous administration took up the highest proportion (90.05％) ; a large proportion of allergic shock was immediate type (80.63％).CONCLUSIONS:Allergic history should be taken in detail before drug use; the indications of drug use should be strictly controlled; the appropriate route of administration should be selected; great importance should be attached to primary disease.Beware of allergic shock induced by antimicrobials and TCM preparation.The rescue equipment should be prepared and the reactions after administration must be closely observed so as to guarantee the safety of drug use.关键词
过敏性休克/不良反应/文献分析Key words
Allergic shock/ Adverse drug reaction/ Literature analysis分类
医药卫生引用本文复制引用
刘峰,刘锐锋..191例药物致过敏性休克不良反应文献分析[J].中国药房,2013,24(30):2854-2856,3.
