摘要
Abstract
Objective:To investigate the influence of laparoscopic surgery and laparotomy for hysterectomy on blood coagulation and fibrinolytic system,prevention and treatment of the postoperative deep vein thrombosis (DVT).Methods:Sixty-five patients of benign uterine disease who underwent hysterectomy were nonrandomly divided into laparoscopic hysterectomy group (32 cases) and open hysterectomy group (33 cases).The values of PT,APTT,TT,FG and D-D before operation,postoperative 0 h and 24 h and 48 h and incidcnce of postoperative DVT were detected respectively.Results:Compared with preoperative data,the APTT of postoperative 0 h and 24 h were significantly lower (P ＜0.05) ;There was no change in the values of PT and TT at the time of postoperative 0 h,24 h and 48 h.Compared with the preoperative value,the D-D value of postoperative 0 h increased significantly (P ＜ 0.05),compared with the postoperative 0 h,the D-D value of postoperative 24 h and 48 h increased further (P ＜ 0.05) ; Compared with preoperative level,the value of FG in postoperative 0 h and 24 h increased significantly (P ＜ 0.05).The parameters between the two groups had no statistical differences (P ＞ 0.05).The incidence of postoperative DVT was similar between the two groups (P ＞ 0.05).Conclusions:Both laparoscopic and open hysterectomy could make the patients at high blood coagulation state,increase the risk of postoperative DVT.Routine preventive measures should be taken for high-risk factors of thrombosis,the discharge time of laparoscopic surgery is earlier,so antithrombotic therapy guidance and close follow-up are suggested.关键词
子宫切除术/腹腔镜检查/剖腹术/静脉血栓形成/病例对照研究Key words
Hysterectomy/Laparoscopy/Laparotomy/Venous thrombosis/Case-control studies分类
医药卫生
