国际病理科学与临床杂志2013，Vol.33Issue(3)：246-250,5.DOI:10.3969/j.issn.1673-2588.2013.03.013
NADPH氧化酶与脑缺血/再灌注损伤
NADPH oxidase and cerebral ischemia/reperfusion injury
摘要
Abstract
Oxidative stress is an important mechanism for cerebral ischemia/reperfusion(I/R) injury.Recently,studies indicate that reactive oxygen species (ROS) from nicotinamide adenine dinucleotide phosphate (NADPH) oxidase play a very important role in oxidative stress following cerebral ischemia/reperfusion.There are some strategies (such as normobaric hyperoxia,ischemic postconditioning) and some medicines (such as apocynin,telmisartan,betulinic acid,galantamine,celastrol) can reduce cerebral ischemia/reperfusion injury through targeting NADPH oxidase.关键词
NADPH氧化酶/活性氧/脑缺血/再灌注损伤Key words
NADPH oxidase/ reactive oxygen species/ cerebral ischemia/reperfusion injury引用本文复制引用
张朝弘..NADPH氧化酶与脑缺血/再灌注损伤[J].国际病理科学与临床杂志,2013,33(3):246-250,5.基金项目
卫生部国家临床重点专科建设项目[财社(2011)170] （2011）
重庆市医学重点学科建设项目[渝卫科教(2007)2].This work was supported by the Clinical Key Subject Contsruction Project of Ministry of Health of China [(2011)170] and the Chongqing Medical Key Discipline Construction Project,P.R.China [(2007)2]. （2007）
