华东师范大学学报（自然科学版）Issue(5)：102-109,8.DOI:10.3969/j.issn.1000-5641.2013.05.013
一种新型T1-T2双模磁共振造影剂的制备及性能研究
Preparation and properties study of a new type of T1-T2 dual mode MRI contrast agent
摘要
Abstract
Alstract:This paper studied the Fe3O4@SiO2@Gd2O(CO3)2 core/shell/shell NPs as a new type of T1-T2 dual model contrast agent for magnetic resonance imaging.The magnetic coupling between Gd2O(COs)2 and Fe3O4 was modulated by the separating SiO2 layer to produce appropriate T1 and T2 signal.The Fe3O4@SiO2@Gd2O(CO3)2 NPs exhibit good biocompatibility,showing great potential for biomedical applications.关键词
Fe3O4@SiO2@Gd2O(CO3)2核/壳/壳纳米粒子/双模磁共振造影剂/生物相容性Key words
Fe3O4@SiO2@Gd2O(CO3)2 core/shell/shell NPs/ dual model contrast agent/biocompatibility分类
数理科学引用本文复制引用
高礼鹏,刘凯,罗春花,李建奇,王依婷,彭晖..一种新型T1-T2双模磁共振造影剂的制备及性能研究[J].华东师范大学学报（自然科学版）,2013,(5):102-109,8.基金项目
国家自然科学基金(60976004) （60976004）
上海市重点基础项目(11JC1403800) （11JC1403800）
上海市教委创新项目(12ZZ041) （12ZZ041）
