吉林中医药2013，Vol.33Issue(8)：821-823,3.
补气化痰方对心肌梗死模型大鼠心功能及血管新生的影响
Effect of Buqi Huatan Prescription(补气化痰方)on Heart Function and Angiogenesis in Rats Model of Myocardial Infarction
摘要
Abstract
Objective Observation of effect of BuQiHuatan fang on rat model of myocardial infarction heart function and angiogenesis.Methods The 60 are male SD rats,were randomly divided into the treatment group (Astragalus Gualou Xiebai Banxia Tang Group),Chinese medicine control group (Gualou Xiebai Banxia Tang Group),the control group of Western Medicine (treatment group),normal group,model group,12 rats in each group SD rats by ligation of the anterior descending branch,establishment of myocardial infarction model,intervention for 28 days,were recorded in rats survival rate,48 hours,28 days of cardiac ultrasound EF,28 days of CD31 expression in muscle,liver and kidney function.Results 28 days survival rate did not differ between rats.28 days in the treatment of rats cardiac ultrasound EF than other groups of rat EF slow decline,there was a statistically significant difference between.And in the immunohistochemical results showed CD31 expression in treatment group than the control group and the model group were higher,there was a statistically significant difference between.There is no significant difference between the groups of liver and kidney function.Conclusion can effectively improve myocardial infarction rat EF value,the mechanism is likely to promote infarction angiogenesis thereby improving improve heart function.关键词
补气化痰方/心肌梗死/心脏功能/血管新生/CD31Key words
Buqi huatan prescription/miocardial infarction/ cardiac function/ angiogenesis/ CD31分类
医药卫生引用本文复制引用
郜俊清,陈弢,于宏梅,孙剑光,赵德强..补气化痰方对心肌梗死模型大鼠心功能及血管新生的影响[J].吉林中医药,2013,33(8):821-823,3.基金项目
国家中医药管理局重点专科建设项目 （）
上海中医药大学附属普陀医院院级课题(2011Z059) （2011Z059）
