解剖学杂志2013，Vol.36Issue(4)：800-803,4.DOI:10.3969/j.issn.1001-1633.2013.04.024
学龄前双生子头面部特征的遗传学分析
Genetic analysis on craniofacial characteristics of pre-school twins
摘要
Abstract
Objective:To analyze genetic and environmental influences on craniofacial development of pre-school twins in China.Methods:16 anthropometric items were measured by using the standard methods of measurement in a total of 101 twin pairs,including 42 monozygotic(MZ) and 59 like-sex dizygotic(DZ) twin pairs aged 3 to 6 years.The quantitative genetic model-fitting and evaluation of variance components were done with Mx,a structural equation modeling package designed for the analysis of variance of genetic,environmental and age effect.Results:The fitting-models of head circumference,head breadth and physiognomic ear breadth were AES without common environment,and others were ACES.After adjusting age,the head circumference,head length,facial breadth,bigonial breadth,physiognomic ear breadth and lip height were 0.84,0.77,0.82,0.65,0.75,0.51 in males and 0.75,0.80,0.79,0.57,0.65,0.56 in females respectively.Sexual genetic difference exited in the upper lip height.Conclusion:Cephalic measurements are influenced by genetic factors more easily than do facial measurements,without sexual influence of genetic variance on most of craniofacial items.关键词
头面部发育/学龄前儿童/双生子/遗传度Key words
craniofacial development/ pre-school children/ twins/ heritability引用本文复制引用
赵曼,李玉玲,陆舜华,刘燕,丁一,郑玉娜,栾天抒..学龄前双生子头面部特征的遗传学分析[J].解剖学杂志,2013,36(4):800-803,4.基金项目
国家自然科学基金(30960167,30371223) （30960167,30371223）
内蒙古自然科学基金(200508010507) （200508010507）
