实用临床医药杂志2013，Vol.17Issue(11)：15-17,3.DOI:10.7619/jcmp.201311005
急诊冠脉介入治疗的急性ST段抬高型心肌梗死患者血浆N末端B型利钠肽原与GRACE评分的相关研究
Relationship between plasma N-terminal pro-brain natriuretic peptide and GRACE risk stratification in patients with acute ST-segment elevation myocardial infarction underwent primary percutaneous coronary intervention
魏洪杰 1芦涤 1金鹏1
作者信息
- 1. 中国石油天然气集团公司中心医院心内科,河北廊坊,065000
- 折叠
摘要
Abstract
Objective To explore the relationship between plasma N-terminal pro-brain natriuretic peptide(NT-proBNP)level and global registry of acute coronary events(GRACE) scores in patients with acute ST-segment elevation myocardial infarction who undergo primary percutaneous coronary intervention.Methods A total of 202 patients with acute ST-segment elevation myocardial infarction(STEMI) who underwent primary percutaneous coronary intervention in our hospital between January 2008 and December 2010 were involved this study.Plasma NT-proBNP level and the GRACE risk score were measured on admission.According the GRACE risk stratification,patients were divided into low-risk group,middle-risk group and high-risk group.There were 68 low -risk patients,78 middle-risk patients and 66 high-risk patients.Results Compared with middlerisk group and low-risk group,lgNT-proBNP level was significantly higher in high-risk group (P＜0.01),and the level of middle-risk group was significantly higher (P＜0.01).lgNT-proBNP was positively correlated with GRACE risk score (r =0.56,P ＜ 0.01).Conclusion On admission plasma NT-proBNP level parallels GRACE risk score in STEMI patients,and NT-proBNP has clinical value to risk evaluation in STEMI patients.关键词
脑钠肽/N氨基末端脑钠肽前体/急性ST段抬高型心肌梗死/急诊冠脉介入/危险性评估Key words
natriuretic peptide/ brain/ acute ST-segment elevation myocardial infarction/primary percutaneous coronary intervention/ risk evaluation分类
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魏洪杰,芦涤,金鹏..急诊冠脉介入治疗的急性ST段抬高型心肌梗死患者血浆N末端B型利钠肽原与GRACE评分的相关研究[J].实用临床医药杂志,2013,17(11):15-17,3.
