实用临床医药杂志2013，Vol.17Issue(11)：119-121,3.DOI:10.7619/jcmp.201311048
血栓弹力图在恶性肿瘤高凝状态诊断中的应用价值
Application value of thromboelastography in diagnosis of hypercoagulability of malignant tumor
摘要
Abstract
Objective To investigate the effect of thromboelastography (TEG) in combination with routine haemostatic assays and ultrasonic doppler examination in deep veins of lower limbs in diagnosis of hypercoagulability of malignant tumor.Methods One hundred and sixty-two malignant tumor patients were examined by TEG,routine haemostatic assays and deep venous ultrasonic examination in lower limbs.According to the results,the patients were classified into deep venous thrombosis group (group A,n =12),erythrocyte aggregation group (group B,n =23) and non-thrombus and erythrocyte aggregation group (group C,n =127).The relationships between reaction time (R value),maximum amplitude value (MA),α angle,D-Dimer,fibrinogen (FIB),fibrinogen degradation products (FDP) and platelet count of three groups were compared.Results There was no statistical significance in each parameter between groups A and B.The R values in groups A and B were significantly lower than that in group C,and the rest of the parameters were significantly higher than that in group C.Conclusion TEG combined with routine haemostatic assays and ultrasonic doppler examination in deep veins of lower limbs can assess the coagulant state in patients with tumor,predict occurred risk of deep venous thrombosis.It can be used to judge whether the patients need anticoagulation,and is one method of reducing the risk of thrombus.关键词
血栓弹力图/凝血试验/恶性肿瘤/静脉血栓Key words
thromboelastography/ haemostatic assays/ malignant tumor/ venous thrombosis分类
医药卫生引用本文复制引用
王莉,裴文仲,杨建东,孔斌,黄希芬,刘义,高芸菲,孔曼..血栓弹力图在恶性肿瘤高凝状态诊断中的应用价值[J].实用临床医药杂志,2013,17(11):119-121,3.基金项目
中国高校医学期刊临床专项资金(11320048) （11320048）
