胃癌组织表皮生长因子受体、增殖细胞核抗原和环氧合酶-2的表达及其与临床病理特征的关系OACSTPCD
Expression of EGFR, PCNA and COX-2 in gastric carcinoma and their relationship with clinicopathological features
目的 探讨胃癌组织表皮生长因子受体(EGFR)、增殖细胞核抗原(PCNA)及环氧合酶-2(COX-2)的表达与其临床病理特征的关系.方法 选取86例胃癌组织标本为研究对象,采用免疫组织化学方法检测EGFR、PCNA及COX-2的表达,探讨三者与胃癌临床病理特征的关系.结果 胃癌组织EGFR、PCNA及COX-2表达的阳性率分别为41.9％、59.3％和44.2％;EGFR及COX-2与肿瘤浸润深度、TNM分期及淋巴转移相关(P＜0.05);PCN…查看全部>>
Objective To explore the expression of EGFR,PCNA and COX-2 in gastric carcinoma and their relationship with clinicopathological features.Methods Eighty-six patients with gastric carcinoma were selected as research subjects.Immunohistochemical method was used to detect expressions of EGFR,PCNA and COX-2.The relationships of EGFR,PCNA and COX-2 with clinicopathological features were analyzed.Results The positive rates of EGFR,PCNA and COX-2 were 41.9％,59.3％ an…查看全部>>
梅晓雷
湖北省孝感市中心医院肿瘤科,湖北孝感,432100
医药卫生
胃癌表皮生长因子受体增殖细胞核抗原环氧合酶-2
gastric carcinoma EGFR PCNA COX-2
《实用临床医药杂志》 2013 (16)
4-5,8,3
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