实用临床医药杂志2013，Vol.17Issue(16)：120-122,3.DOI:10.7619/jcmp.201316047
新生儿缺氧缺血性脑病神经发育预后的影响因素
Predictive factors for prognosis of neurodevelopment in term neonates with hypoxic-ischemic encephalopathy
黄梅英 1庞国象 1麦水强1
作者信息
- 1. 广东省深圳市龙岗区人民医院儿科,广东深圳,518172
- 折叠
摘要
Abstract
Objective To explore predictive factors to evaluate the neurodevelopmental prognosis in term neonates with hypoxic-ischemic encephalopathy(HIE).Methods Electroencephalography,neuroimaging,periodic neurological exams and a developmental test at 44-48months after discharge from the hospital were performed on 50 term neonates with HIE.The dead and abnormally developed neonates were taken as problematic prognosis group,and well developed neonates taken as good prognosis group.Logistic analysis was made of risk factors affecting neurodevelopmental prognosis.Results Normal/mildly abnormal neonatal electroencephalography was correlated with favorable outcome,particularly if neuroimaging was normal.The cranial MRI sensitivity and specificity was higher,and the predictive value was higher.Moderate/severely abnormal electroencephalography and multifocaI/diffuse cortical or deep gray matter lesions were correlated with poor outcomes.Conclusion Neurological developmental scores,abnormal electroencephalogram and brain imaging are predictive risk factors to evaluate the neurodevelopmental prognosis in term neonates with HIE.关键词
脑电图/新生儿缺氧缺血性脑病/核磁共振/神经发育预后Key words
electroencephalography/ hypoxic ischemic encephalopathy/ magnetic resonance imaging/ enurodevelopmental outcome分类
医药卫生引用本文复制引用
黄梅英,庞国象,麦水强..新生儿缺氧缺血性脑病神经发育预后的影响因素[J].实用临床医药杂志,2013,17(16):120-122,3.
