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CgA和PCA3的表达在前列腺癌患者诊断中的应用研究

杜雄 李延新 周延军 张春莉

昆明医科大学学报2013,Vol.34Issue(7):69-71,3.
昆明医科大学学报2013,Vol.34Issue(7):69-71,3.

CgA和PCA3的表达在前列腺癌患者诊断中的应用研究

The Clinical Application of CgA and PCA3 Expressions (in Blood and Urine) in Diagnosis of 62 Cases of Prostatic Cancer

杜雄 1李延新 1周延军 1张春莉1

作者信息

  • 1. 延安大学附属医院病理科,陕西延安716000
  • 折叠

摘要

Abstract

Objectives To discuss CgA and PCA3 expressions' (in blood and urine) and their clinical application in diagnosis of prostatic cancer.Methods 62 patients affected with prostatic cancer and 62 persons having health examinations were randomly selected and classified into two groups.Those affected with prostatic cancer were in the experimental group and those having health-examinations were in the control group.CgA and PCA3 expressions in blood and urine were quantitatively measured to discuss the clinical value in diagnosis of prostatic cancer.Results Positive expression rates of CgA and PCA3 in the experimental group were obviously higher than those of the control group.CgA value in the experimental group increased as the disease progressed,whereas there were no changes basically in the control group (P<0.05).Conclusions CgA and PCA3 specificity and positive expressions can provide reliable evidence for diagnosis of prostatic cancer,so that they can be used as a tumor marker to improve diagnostic sensitivity of prostatic cancer and is worthy of clinical promotion.

关键词

CgA/PCA3/前列腺癌/临床应用

Key words

Plasma chromaffin granule proteins/ Prostate cancer antigen/ Prostatic cancer/ Clinical application

分类

医药卫生

引用本文复制引用

杜雄,李延新,周延军,张春莉..CgA和PCA3的表达在前列腺癌患者诊断中的应用研究[J].昆明医科大学学报,2013,34(7):69-71,3.

基金项目

延安大学附属医院院内科研基金资助项目(2012.YD.FYY326) (2012.YD.FYY326)

昆明医科大学学报

OACSTPCD

1003-4706

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