临床口腔医学杂志2013，Vol.29Issue(7)：405-407,3.DOI:10.3969/j.issn.1003-1634.2013.07.008
功能矫形前伸下颌对大鼠咬肌TrkB表达影响的研究
The changes of TrkB expression in masseter muscles of rats after functional mandibular advancement
李雪 1杨林2
作者信息
- 1. 西安医学院 陕西 西安710021
- 2. 西安交通大学口腔医院正畸科 陕西 西安710004
- 折叠
摘要
Abstract
Objective:To investigate the changes of Tyrosine kinase receptor-B (TrkB) expression in masseter muscles fibers of adolescent rats after functional mandibular advancement.Method:Forty 4-week-old male Sprague-Dawley (SD)rats were randomly divided into experimental and control groups.The mimic functional appliances were used in experimental groups,and the rats of two groups were killed on 3rd,7th,14th,21th day.Immunohistochemistry staining method and reverse transcription polymerase chain reaction (RT-PCR) were used to detect the TrkB expression of muscle fibers in rat masseter muscles.Result:The expression of TrkB in 3d-and 7d-groups in experimental groups were higher than that in control groups,but made no significance,the expression of TrkB were significantly higher in experimental 14d-and 21d-groups than that in control 14d-and 21d-groups.Conclusion:Accompanying the functional orthopedics,TrkB expression is progressively increased,which may contribute to the proprioceptive adaptation to masseter muscles rebuilding.关键词
功能性前伸下颌/咬肌/酪氨酸激酶受体-B (TrkB)Key words
functional mandibular advancement/ masseter muscles/ TrkB分类
医药卫生引用本文复制引用
李雪,杨林..功能矫形前伸下颌对大鼠咬肌TrkB表达影响的研究[J].临床口腔医学杂志,2013,29(7):405-407,3.
