环境与职业医学2013，Vol.30Issue(8)：601-603,3.
职业性锰暴露对锰冶炼厂男性工人认知能力的影响
Effect of Occupational Manganese Exposure on Cognitive Function in Male Smelting Workers
摘要
Abstract
[Objective] To explore the changes of cognitive function in male smelting workers with exposure to various levels of manganese (Mn) and its possible influencing factors.[Methods] A total of 240 male smelting workers were chosen from a Mn smelter in Guangxi and divided into high (86 workers) and low (154 workers) Mn exposure groups according to a cumulative exposure index (CEI); 240 male workers of a sugar refinery in the same region were selected as the control group.All participants were required to complete questionnaires to collect general information and evaluate cognitive fimction by the Montreal Cognitive Assessment (MoCA) test (Beijing version).[Results] There was a negative association between cognitive function and the Mn cumulative exposure levels in male smelting workers (r=-0.324,P ＜0.05).The MoCA scores of the 2 exposure groups were remarkably lower than that of the control group (P＜0.01),and the group with high Mn exposure level reported significantly lower scores than the group with low Mn exposure level (P ＜ 0.05),after adjusted age,marital status,and other related variables.The results of multiple linear regression analysis showed that the worker's cognitive function was significandy affected by age,education,Mn exposure level,and smoking (P＜0.05).[Conclusion] Occupational Mn exposure might decrease the cognitive function in male smelting workers.Moreover,the cognitive function could also be affected by age,education,and smoking.关键词
男性工人/锰暴露/认知能力/蒙特利尔认知评估/锰累积暴露指数Key words
male workers/manganese exposure/cognitive function/Montreal Cognitive Assessment/manganese cumulative exposure index分类
医药卫生引用本文复制引用
刘静,卿利,李琴,陈康成,曾小云,邱毅,陈小红,梁林涵,邹云锋..职业性锰暴露对锰冶炼厂男性工人认知能力的影响[J].环境与职业医学,2013,30(8):601-603,3.基金项目
国家自然科学基金资助项目(编号:81072320、81060234) （编号:81072320、81060234）
广西自然科学基金资助项目(编号:2011jjA40294) （编号:2011jjA40294）
