摘要
Abstract
Objective:To analyze the serum levels of osteoprotegerin in the patients with Coronary artery calcification, and to explore the relevance between above mentioned.Methods: 50 cases patients were collected in the people’s hospital of Zhalantun, All patients were screened for carotid plaque by using 16-slice spiral CT. According to the results, patients were classed as follows:the Coronary artery calcification group (n=30),no Coronary artery calcification group (n=20), General data of each patient, including gender, age, blood fat and blood glucose ,blood pressure, etc, were measured within 24 hours after admission to hospital, serum OPG levels were measured, coronary artery calcification scores were counted according to the result of The 16-slice spiral CT were used to analyze mentioned of the serum levels of osteoprotegerin and Coronary artery calcification. Results:(1)Serum OPG levels were significantly higher in the Coronary artery calcification patients than the control patients (p<0.01);(2)The scores of CACwere positively correlated with OPG levels (p<0.01);(3)Fasting plasma glucose (FPG) and LDL levels were significantly higher in CAC patients than the control patients (p<0.01, P<0.05).Conclusions: Serum OPG were significantly higher in CAC patients. Serum OPG levels were related with the scores of CAC, with the scores increased and OPG levels rised, this means that the marker has close relation with lesions progress of CAC. And the levels of OPG are significantly and positively correlated to FPG and LDL, which signifies in the development of CAC.关键词
骨保护素/冠状动脉钙化/冠状动脉钙化积分Key words
Osteoprotegerin/Coronary artery calcification/Coronary artery calcification scores分类
医药卫生
