生物骨科材料与临床研究2013，Vol.10Issue(3)：46-49,后插5-后插6,6.DOI:10.3969/j.issn.1672-5972.2013.03.013
聚醚醚酮/纳米羟基磷灰石生物材料对MG-63细胞增殖作用
Study on MG-63 cells proliferation for PEEK/HA composite
摘要
Abstract
Objective To prepare PEEK/HA composite materials and,study MG-63 cells Proliferation effect of the composite materials at different periods and under different concentrations and Determine MG-63 cell adhesion rate of the material.Method Based on the polycondensation of polyether-ether-ketone,adding 10％,20％ hydroxyapatite blending into PEEK,to prepare biological composite materials.Using Inverted fluorescence microscope to observe cell morphology MTT method was used to study the cell proliferation in various conditions.Results The materials cytotoxicity level at 0 or Ⅰ,which indicates that PEEK/HA composites are non-toxic to MG-63 cells.In a concentration of 8 mg/ml,the material has an obvious role in cell proliferation.In a concentration of 64 mg/ml concentration,the effect of PEEK composites on cell proliferation is minimum.Cell adhesion rate increases with an increase of HA content in PEEK/HA material,HA can improve cell adhesion to the materials.Conclusion PEEK/HA composites have no obvious toxicity to MG-63 cells.关键词
PEEK/HA复合材料/MG-63细胞/细胞毒性/黏附率Key words
PEEK/HA composite/ MG-63 cells/ Proliferation/ Cytotoxicity/ Cell adhesion分类
通用工业技术引用本文复制引用
倪卓,王应,刘士德,董慧恩,苏聪聪,刘学..聚醚醚酮/纳米羟基磷灰石生物材料对MG-63细胞增殖作用[J].生物骨科材料与临床研究,2013,10(3):46-49,后插5-后插6,6.基金项目
深圳大学应用技术开发项目(201223) （201223）
广东省大学生创新实验项目(1059012024) （1059012024）
