实用肝脏病杂志2013，Vol.16Issue(3)：245-247,3.DOI:10.3969/j.issn.1672-5069.2013.03.017
41例巨大原发性肝癌三维适形放射治疗临床观察
A clinical study of three-dimensional conformal radiotherapy in forty-one patients with massive primary liver cancer
芦东徽 1钱立庭 2费振乐 3胡宗涛 3郝文胜3
作者信息
- 1. 230031 合肥市 安徽医科大学解放军临床学院
- 2. 安徽医科大学附属省立医院放疗中心
- 3. 合肥市解放军第105医院肿瘤中心
- 折叠
摘要
Abstract
Objective To evaluate the efficacy of three-dimensional conformal radiotherapy (3D-CRT) in the treatment of patients with massive primary liver cancer.Methods Forty-one patients with massive primary liver cancer were treated with 3D-CRT at 200cGy factions to a total doses of 3500cGy to 5000cGy (mean 3960cGy).All patients were followed-up for 6 to 40 (21±5)months.Short-term efficacy was evaluated according to WHO tumor evaluation standard.All patients were checked-up at each visit for the blood routine,liver function,AFP,BUS,CT and MRI.Results 41 patients accomplished the treatment.The local response rates were 70.7％ (29/41)after treatment in 16 with PR,in 13 with SD.The 1,2 year survival rates were 29.27％,19.51％.In the multivariate analysis,the therapeutic effects,metastasis,clinical staging and the diameter of the tumors presented prognostic significance for overall survival(P＜0.05).The total dose and Child grade did not present prognostic significance for overall survival (P≥0.05).Conclusions 3D-CRT is appropriate for massive primary hepatic carcinomas and can prolong the survival times.关键词
原发性肝癌/三维适形放射治疗/疗效Key words
Hepatic carcinomas /Three-dimensional conformal radiotherapy/ Curative effect引用本文复制引用
芦东徽,钱立庭,费振乐,胡宗涛,郝文胜..41例巨大原发性肝癌三维适形放射治疗临床观察[J].实用肝脏病杂志,2013,16(3):245-247,3.
