实用医学杂志2013,Vol.29Issue(10):1600-1602,3.DOI:10.3969/j.issn.1006-5725.2013.10.023
丙泊酚与依托咪酯靶控输注在支气管镜麻醉效果的比较
Comparison of Bronchoscopy Anesthesia Effects of Target Controlled Infusion by Propofol or Etomidate
摘要
Abstract
Objective To compare the effects of propofol or etomidate combining remifentanil target controlled infusion in bronchoscopy anesthesia.Methods 60 patients (ASA Ⅰ-Ⅱ grade)selectively undergoing bronchoscopy were randomly divided into propofol group (group P) and etomidate group (group E) (30 in each group).Group P received 4.0 μg·ml-1 propofol and 6.0 ng·ml-1 remifentanil and group E received 1.0 μg·ml-1 etomidate and 6.0 ng·ml-1 remifentanil as induction.Bronchoscope was inserted when the above medicine was adjusted at target concentration.MAP,HR and SpO2 before oxygen uptaking(T0),reduction starting 1 min (T1),bronchoscope inserting (T2),1 min post-inserting (T3),2 min post-inserting (T4),5min post-inserting (T5) and operation end.(T6).Detecting time,sleeping time,and the adverse events during anesthesia period were recorded.Results Revival time in group E prolong than group P.At T2 in group E,MAP was highcr,hypotension rate and pain rate lower,while rates of nausea and vomiting higher.Conclusion Etomidate combining remifentanil target controlled infusion in bronchoscopy anesthesia is able to obtain more steady blood pressure but higher rate of nausea and vomiting compared with propofol.While propofol reduction was much more satisfied.关键词
丙泊酚/依托咪酯/靶控输注/支气管镜检查Key words
Propofol/Etomidate/Target Controlled Infusion/Bronchoscopy引用本文复制引用
梁幸甜,李渭敏,廖美娟,杨承祥..丙泊酚与依托咪酯靶控输注在支气管镜麻醉效果的比较[J].实用医学杂志,2013,29(10):1600-1602,3.