天然产物研究与开发2013，Vol.25Issue(8)：1022-1026,5.
壳寡糖镧配合物的抑菌活性及其与牛血清白蛋白的相互作用
Antibacterial Activities of Oligchitosan-La Complex and Its Interaction with Bovine Serum Albumin
摘要
Abstract
The oligchitosan-La complex was synthesized from oligchitosan with LaCl3,and its structure and property were characterized by IR spectrum,UV spectrun and TG-DTG methods.In addition,the antibacterial activity of oligchitosanLa against Staphyloccocus aureus (St.aureus) and Escherichia coli (E.coli) was investigated using inhibition zone method.Moreover,the interaction between oligchitosan-La and bovine serum albumin (BSA) was studied by UV spectrum,fluorescence spectrum and cyclic voltammetry (CV) methods.The results showed that oligchitosan and oligchitosan-La possessed antibacterial activities,and the antibacterial activity of oligchitosan-La was stronger than that of oligchitosan.The oligchitosan-La complex quenched the fluorescence of BSA and it was static quenching.The binding constant and binding sites was 6.35 × 104 L/mol and 1.29 at room temperature,respectively.关键词
壳寡糖/镧/抑菌活性/牛血清白蛋白/相互作用Key words
oligchitosan/ La (Ⅲ)/antibacterial activity/ bovine serum albumin /interaction分类
轻工纺织引用本文复制引用
冯小强,李小芳,杨声..壳寡糖镧配合物的抑菌活性及其与牛血清白蛋白的相互作用[J].天然产物研究与开发,2013,25(8):1022-1026,5.基金项目
天水师院物理无机化学重点学科基金项目(ZD0840) （ZD0840）
天水师院"青蓝"人才工程资助项目 （）
