物理化学学报Issue(11)：2735-2744,10.DOI:10.3866/PKU.WHXB201207162
多肽抑制剂抑制淀粉质多肽42构象转换的分子动力学模拟和结合自由能计算
Molecular Dynamics Simulation and Binding Free Energy Calculation of the Conformational Transition of Amyloid Peptide 42 Inhibited by Peptide Inhibitors
摘要
Abstract
10.3866/PKU.WHXB201207162关键词
分子动力学模拟/阿尔茨海默病/淀粉质多肽/多肽抑制剂/构象转换Key words
Molecular dynamics simulation/Alzheimerʹs disease/Amyloid peptide/Peptide inhibitor/Conformational transition分类
化学化工引用本文复制引用
董晓燕,都文婕,刘夫锋..多肽抑制剂抑制淀粉质多肽42构象转换的分子动力学模拟和结合自由能计算[J].物理化学学报,2012,(11):2735-2744,10.基金项目
The project was supported by the National Natural Science Foundation of China (20906068,21076149), National Key Basic Research Program of China (973)(2009CB724705), and Natural Science Foundation of Tianjin from Tianjin Municipal Science and Technology Commission, China (10JCYBJC04500).国家自然科学基金(20906068,21076149),国家重点基础研究发展规划项目(973)(2009CB724705)和天津市科委自然科学基金(10JCYBJC04500)资助 （20906068,21076149）
