中国动脉硬化杂志2013，Vol.21Issue(7)：631-634,4.
稳定型冠心病患者血浆内皮微粒与动脉弹性的关系
Relationship of Endothelial Microparticles and Arterial Elasticity in Patients with Stable Coronary Artery Disease
张子新 1李超君 1余陆娇1
作者信息
- 1. 中国医科大学附属第一医院心内科,辽宁省沈阳市110001
- 折叠
摘要
Abstract
Aim To investigate the association of endothelial microparticle (EMP) and brachial-ankle pulse wave velocity (baPWV) in patients with stable coronary artery disease (CAD).Methods 50 patients with stable coronary artery disease and 20 healthy volunteers were studied.Flow cytometer was used to measure levels of EMP (CD31 + /CD42b-) in circulation and baPWV was measured to assess the status of arterial elasticity.Results The levels of EMP were higher in patients with stable CAD than that of healthy volunteers (1 748.4 + 102.1 particles/μL vs 847.4 ±86.4 particles/μL,P ＜0.01),and baPWV was faster in patients with stable CAD than that of healthy volunteers (1931.1 ± 328.3 cm/s vs 1 532.1 ± 147.3 cm/s,P ＜ 0.01).There was a positive correlation between the level of EMP and baPWV in stable CAD (r =0.42,P ＜ 0.01).Conclusions Patients with stable CAD had higher EMP and faster baPWV than those of healthy volunteers,and there was positive correlation between EMP and baPWV.EMP was an independent influencing factor to arterial elasticity.关键词
冠心病/内皮微粒/肱踝脉搏波传导速度Key words
Coronary Artery Disease/ Endothelial Microparticles/ Brachial-ankle Pulse Wave Velocity分类
医药卫生引用本文复制引用
张子新,李超君,余陆娇..稳定型冠心病患者血浆内皮微粒与动脉弹性的关系[J].中国动脉硬化杂志,2013,21(7):631-634,4.
