中国动脉硬化杂志2013，Vol.21Issue(8)：737-740,4.
不同类型肥胖对原发性高血压患者动脉僵硬度的影响
Effect of Different Obese Type on Arterial Stiffness in Essential Hypertension
摘要
Abstract
Aim To investigate the effect of different obese type on arterial stiffness in essential hypertension.Methods The basic information was collected in a total of 776 essential hypertensive patients.According to body mass index (BMI) and waist circumference (WC) level,all patients were divided into four groups,namely,normal BMI and normal waist circumference group (I group,n =194),normal BMI and elevated waist circumference group (Ⅱ group,n =195),excessive BMI and normal waist circumference group (Ⅲ group,n =196),excessive BMI and elevated waist circumference group (Ⅳgroup,n =191).Brachial ankle pulse wave velocity (BaPWV) and ankle-brachial blood pressure index (ABI) were observed in all patients.Arterial stiffness index (AI) was calculated using the blood lipid of all hypertension patients.Results BaPWV (2120 ± 263 mm/s) and AI (3.35 ± 0.87) in Ⅳ group were significantly higherthan Igroup(P＜0.01),ⅡgroupandⅢgroup(P＜0.05).ABI(0.72±0.15) in Ⅳ group were significantly lower than Ⅰ group (P ＜ 0.01),Ⅱ group and Ⅲ group (P ＜ 0.05).There were no statistical differences between Ⅱgroup and Ⅲ group in ABI and AI (P ＞ 0.05).Results of 2 x 2 factorial analysis showed that there was a distinctive and synergistic effect between excessive BMI and elevated waist circumference on arterial stiffness.Conclusion Arterial elasticity function was aggravatedly damaged in essential hypertension in patients with abdominal obesity.Excessive BMI and elevated waist circumference had interaction and synergistic effect on the damage of arterial elasticity function.关键词
腹型肥胖/动脉僵硬度/高血压Key words
Abdominal Obesity/ Arterial Stiffness / Hypertension分类
医药卫生引用本文复制引用
宋洪斌,刘振东,路方红,刁玉涛,张华,赵颖馨,孙尚文,齐在文..不同类型肥胖对原发性高血压患者动脉僵硬度的影响[J].中国动脉硬化杂志,2013,21(8):737-740,4.基金项目
山东省自然科学基金项目(ZR2011HQ053,ZR2009CL029) （ZR2011HQ053,ZR2009CL029）
