中国动脉硬化杂志2013，Vol.21Issue(8)：755-757,3.
高危后循环短暂性脑缺血发作患者CD4+ CD25+调节性T细胞检测及意义
Significance of Change of CD4 + CD25 + Regulatory T Cells in Patients with High-risk Transient Ischemic Attack in Posterior Circulation
摘要
Abstract
Aim To explore the significance of the change of CD4 + CD25 + regulatory T cells (Treg) in patients with high-risk transient ischemic attack (TIA) in posterior circulation.Methods The frequencies of Treg were detected in 21 patients with high-risk TIA in posterior circulation,19 patients with dizziness syndrome and 20 health adults by flow cytometer.Results The frequencies of Treg were found to be significantly lower in patients with high-risk TIA in posterior circulation (5.66％ ± 1.91％) than those of dizziness syndrome (9.18％ ±2.26％) and health adults (9.21％± 2.71％).Conclusions The frequencies of Treg decrease in patients with high-risk TIA in posterior circulation.The decrease of Treg may lead to the breakdown of autoimmune tolerance and participate in the progression of atherosclerosis,which could be one of the pathogenesis of the high-risk TIA in posterior circulation.关键词
短暂性脑缺血发作/CD4+ CD25+调节性T细胞/自身免疫/动脉粥样硬化Key words
Transient Ischemic Attack/ CD4 + CD25 + Regulatory T Cell/ Autoimmune/ Atherosclerosis分类
医药卫生引用本文复制引用
杨汀,樊光辉,刁波..高危后循环短暂性脑缺血发作患者CD4+ CD25+调节性T细胞检测及意义[J].中国动脉硬化杂志,2013,21(8):755-757,3.基金项目
2010年度军队中医药科研专项课题(10ZYZ117) （10ZYZ117）
