中国美容医学2013,Vol.22Issue(15):1616-1618,3.
口服普萘洛尔治疗严重婴幼儿血管瘤的临床观察
Clinical study on the treatment of oral propranolol treatment for severe infantile hemangioma
王书军 1陈濛 1于海洲 1严晓鸥 1刁永力1
作者信息
- 1. 盐城市第一人民医院烧伤整形科 江苏盐城 224001
- 折叠
摘要
Abstract
Objective To estimate the efficacy and safety of propranolol treatment for severe infantile hemangioma.Methods From Sept.2009 to Sept.2012,34severe infantile hemangioma patients were treated with propranolol in our department.The daily dose of propranolol was increased from 1 mg/kg at the first day to 1.5mg/kg at the second day,and to 2mg/kg at the third day.The propranolol was given twice a day.The response to treatment at 1 week,1 month and at the end of treatment was evaluated.Results One week after treatment beginning,the hemangioma growth was controlled in all patients.The accelerated regression was achieved in 97.1%(33/34) of patients after 1 month of treatment and at the end of treatment.Ulceration was occurred in 3 cases before treatment,which was healed after treatment for 2 months.Diarrhea or appetite decrease was happened in 8.8%(3/34)of patients.Rebound growth of lesion was noticed in 26.5% (9/34) of patients.Conclusions Propranolol is effective in the treatment of infantile hemangioma with minor side effects.We suggest it should be used as the first-line treatment.关键词
普萘洛尔/婴幼儿血管瘤Key words
propranolol/ infantile hemangioma分类
医药卫生引用本文复制引用
王书军,陈濛,于海洲,严晓鸥,刁永力..口服普萘洛尔治疗严重婴幼儿血管瘤的临床观察[J].中国美容医学,2013,22(15):1616-1618,3.