中国内镜杂志2013，Vol.19Issue(4)：348-353,6.
应用Volume软件测定肺减容动物实验中肺容积变化的研究
Volume software measuring pulmonary volume of lung volume reduction in animal experiment
摘要
Abstract
[Objective] To evaluate the value of volume software of multi-slice spiral CT in measuring pulmonary volume of lung volume reduction in animal experiment.[Methods] Eight young pigs (16～22 kg) were randomly divided into experimental group and control group.Each pig was treated with biological lung volume reduction under fiberoptic bronchoscope guide before operation and one week after,one month and three month after the operation,its lung volume was measured respectively by volume software,then relation with its morphology and histopathology was analyzed and the effectiveness of lung volume reduction was evaluated.[Result] The control group with 4 young pigs whose right lung volume / total lung declined from (48.9±4.7)％ to (48.2±5.7)％ after three months were no significant differences (P ＞0.05).But there were straightly reduced from (57.9±1.6)％ to (49.6± 2.65)％ in experimental group with other 4 young pigs (P ＜0.05).Meanwhile three months later its volume of target lung dramatically decreased,following pulmonary fibrosis in varying degrees,which extremely consisted with the imaging changes.Yet the control group with 4 pigs had no significant changes in morphology and histopathology,even preoperative and postoperative CT scans.[Conclusion] It is a simple,rapid,accurate and no trauma method estimated by volume software supplied by multi-slice spiral CT for measuring pulmonary volume of lung volume reduction in animal experiments.关键词
肺减容术/动物/肺容积/多螺旋CT/Volume软件Key words
lung volume reduction/ animal/ pulmonary volume/ multi-spiral CT/ Volume software分类
医药卫生引用本文复制引用
李文涛,郑厚文,黎雨,傅钰雁,柳广南..应用Volume软件测定肺减容动物实验中肺容积变化的研究[J].中国内镜杂志,2013,19(4):348-353,6.基金项目
本研究受广西自然基金项目资助(桂科自0640099) （桂科自0640099）
