摘要
Abstract
[Objective] To evaluate the safety,validity and feasibility of hypertensive patients undergoing analgesia colonoscopy.[Method] 300 hypertensive patients accepted colonoscopy were randomly divided into group A (n=1S0) and group B (n=150).Patients in group A received routine treatment and the group B accepted analgesia colonoscopy.During the examination the propofol (1.5-2.0 mg/kg) and remifetanil (0.Sg-1.0mg/kg) was used in group B.Colonoscopy inserting began when patient's lids relax dully,stopped infusion when colonoscopy reached ileocecal region.The changes of mean artery pressure,heart rate,respiratory rate and blood oxygen saturation were recorded and analyzed during operation and after operation.[Result] Compared with the before operation,the mean artery pressure and heart rate are upgrade obviously in group A (P ＜0.01),but which were downgrade after succession of anesthesia in group B (P ＜0.01).There were no significant changes of MAP,RR,HR during the whole colonoscopy inserting process.Compared with the group A,the MAP,HR,RR were obviously downgrade in group B at each observation spot (P ＜0.01),however,there was no significant difference about SPO2,operation time in two group.The success rate of operation in group B was higher than group A obviously (P ＜0.01).About adverse reaction,the incidence rate of abdominal pain,abdominal distension and body movement in group A was higher than group B (P ＜0.01),but,the nausea,vomiting,dizziness,bradycardia in group B was more common (P ＜0.01).Successful rate of colonoscopy in group B (98.7％) was higher than that in group A (92％),however,the operation time of colonoscopy was no significant difference in two groups.During colonoscopy operation adverse effect in group A was lower than that of the norm al group and the group A patients were more comfortable.[Conclusion] Analgesia colonoscopy is applicable and safe in hypertension patients.关键词
高血压/结肠镜检查/丙泊酚/芬太尼Key words
colonoscopy/ hypertension/ propofol/ remifetanil分类
医药卫生
