中国人兽共患病学报2013，Vol.29Issue(7)：665-670,6.DOI:10.3969/cjz.j.issn.1002-2694.2013.07.005
2012年1株南美洲输入登革1型病毒的基因组特征
Genomic characterization of a dengue-1 virus originated from South America, 2012
摘要
Abstract
During the past decade,dozens of imported dengue fever cases have been annually notified in Fujian Province,China,most infections are associated with travel histories in Southeast Asia.In this study,one dengue-1 strain was isolated from a Chinese patient returned from Suriname recently,the full-length viral genome was sequenced,hence,its genetic characterization was analyzed.It was indicated from phylogenetic analysis that this strain was distinct from current South American strains available,while BLAST analysis revealed high homology with strains circulating in Southeast Asia.Therefore,it is highlighted that continuous surveillance for circulating dengue viruses,especially with partial or complete genome sequences,would facilitate in tracking viral transmission routes and monitoring ongoing microevolution in dengue strains worldwide.关键词
登革病毒/基因组序列/种系发生分析Key words
dengue virus/ genome sequence/ phylogenetic analysis分类
医药卫生引用本文复制引用
张拥军,王金章,黄萌,吴生根,翁育伟..2012年1株南美洲输入登革1型病毒的基因组特征[J].中国人兽共患病学报,2013,29(7):665-670,6.基金项目
Supported by the Natural Science Foundation of Fujian Province (No.2011J01126),and the Innovative Projects in Medical Sciences of Fujian Province (No.2012-CXB-13) （No.2011J01126）
福建省自然科学基金项目(2011J01126),福建医学创新课题(2012-CXB-13)资助 （2011J01126）
