中国药物经济学Issue(5):126-128,3.
文拉法辛与阿米替林治疗年轻女性首发抑郁症对照研究
The Efficacy and Tolerability of Venlafaxine and Amitriptyline in Treatment of young women Patients with First episode Depression
王爱梅 1周峰 1唐志辉1
作者信息
- 1. 福州市精神病人疗养院,福建福州 350008
- 折叠
摘要
Abstract
Objective Study on treatment of first-episode depression Vin Rafa Sin young women the effectiveness and safety of. Methods A randomized, single-blind control ed method, 120 cases of 18~40 years old episode depression female patients were divided into study group(venlafaxine)and control group(amitriptyline),8 weeks. Results Research group, the effective rate was 59.7%,87.1%respectively, the control group markedly effective rate was 60.3%, effective rate was 86.2%, the two drugs had no significant difference (P>0.05). Second weeks after the treatment, the HAMD study group reduction rates higher than those in control group (t=2.68, P<0.05). After fourth weeks treatment, the research group TESS score lower than those in the control group, the two drugs was significant difference (P<0.05). Conclusion Vin Rafa Sin treatment of young female first-episode depressive effective and less adverse reaction, compliance is good, good tolerance.关键词
文拉法辛/阿米替林/年轻女性/抑郁症Key words
Venlafaxine slow-soluble/Amitriptyline/Young women/Depression引用本文复制引用
王爱梅,周峰,唐志辉..文拉法辛与阿米替林治疗年轻女性首发抑郁症对照研究[J].中国药物经济学,2012,(5):126-128,3.