中国医学创新Issue(29)：8-9,10,3.DOI:10.3969/j.issn.1674-4985.2012.29.004
紫杉醇联合卡铂化疗并同步放疗在中晚期宫颈癌治疗中的临床疗效分析
Analysis of Clinical Efficacy of Paclitaxel and Carboplatin Chemotherapy in Combination with Radiotherapy in the Treatment of Advanced Cervical Cancer
高桂臣1
作者信息
- 1. 山东省新泰市中医院 山东 新泰 271200
- 折叠
摘要
Abstract
Objective:To investigate the clinical efficacy of paclitaxel and carboplatin chemotherapy in combination with radiotherapy in the treatment of advanced cervical cancer. Method:125 cases of advanced cervical cancer patients in our department recently,according to the treatment program,they were divided into radiotherapy combined with paclitaxel and carboplatin combination chemotherapy in the observation group and for control group,only treatment with radiotherapy alone. The two groups were observed near future and far clinical effects and analysis of the two groups the incidence of complications. Result:Paclitaxel and carboplatin concurrent with radiotherapy treatment in the observation group,complete remission rate, overall efficiency were 17.3%,60.0%,which were significantly higher than 6.0%,38.0%;follow-up found that 3-year survival rate of the observation group,5-year survival rates were 77.3%,60.0%respectively;local recurrence rate,distant metastasis rates were 14.7%,9.3%,meaned survival time (3.5±2.6) years,which were significantly better than the control group (P<0.05). The incidence of toxicity of the observation group was significantly higher. Conclusion:Paclitaxel and carboplatin radiotherapy treatment of patients with advanced cervical cancer can significantly enhance the therapeutic effect,prolonging patients’survival time.关键词
紫杉醇/卡铂/放疗/中晚期宫颈癌Key words
Paclitaxel/Carboplatin/Radiotherapy/Advanced cervical cancer引用本文复制引用
高桂臣..紫杉醇联合卡铂化疗并同步放疗在中晚期宫颈癌治疗中的临床疗效分析[J].中国医学创新,2012,(29):8-9,10,3.
