中国医学创新Issue(31):159-161,3.DOI:10.3969/j.issn.1674-4985.2012.31.104
注意力缺陷多动障碍分子影像学进展
Molecular Imaging Advances in Attention Deficit Hyperactivity Disorder
摘要
Abstract
The article objectively reviewed advances of molecular imaging in ADHD,including SPECT and PET. Also its morphological anatomy was systematically summarized. Abnormalities of the fronto-striatal circuit had been demonstrated,involved prefrontal cortex area regional cerebral blood flow(rCBF)decreasing,Striatal dopamine transporter density increasing,prefrontal area and striatum brain volumes diminishing,predominantly at the right hemisphere,which was the pivotal pathophysiological foundation of this disorder. While compensatory mechanism and comorbid disorders may provide an interpretation to the others abnormal areas of brain like temporal lobe、parietal lobe、occipital lobe and cerebellum. Accurately,molecular imaging has a significant value in diagnosis and evaluating therapeutic effect due to the limitation of anatomic structure images.关键词
注意力缺陷多动障碍/分子影像/SPECT/PETKey words
Attention deficit hyperactivity disorder/Molecular imaging/SPECT/PET引用本文复制引用
张嘉辉,赵正勤,贾少微,杨红杰..注意力缺陷多动障碍分子影像学进展[J].中国医学创新,2012,(31):159-161,3.基金项目
深圳市科技项目(编号:201202020) (编号:201202020)