中国医学创新Issue(36)：1-3,4,4.DOI:10.3969/j.issn.1674-4985.2012.36.001
33例颈及胸上段食管癌后程调强适形放疗疗效观察
Treatment Outcome of Late-course Intensity Modulated Radiotherapy for 33 Cases of Cervical and Upper Thoracic Esophageal Carcinoma
李广虎 1马军 1刘云琴 1赵于飞 1张红雁1
作者信息
- 1. 安徽医科大学附属省立医院 安徽 合肥 230001
- 折叠
摘要
Abstract
Objective:To evaluate the therapeutic effect of late-course intensity modulated radiotherapy in patients with cervical and upper thoracic esophageal carcinoma.Method:From January 2005 to August 2010,33 cases of cervical and upper thoracic esophageal carcinoma were treated with late-course intensity modulated radiotherapy.All patients underwent conventional radiotherapy of 30 Gy in 15 fractions with“T”shape radiation fields followed by late-course intensity modulated radiotherapy,with total dose of 56~70 Gy(median 62 Gy).All patients received prophylactic irradiation of 50 Gy to the bilateral supraclavicular regions.Result:Complete response(CR)rate and partial response(PR)rate were 36.3%(12/33)and 60.6%(20/33), respectively.The 1-year and 2-year local control rate were 83.2% and 71.6%,respectively.The 1-year and 2-year overall survival rate were 69.7% and 62.4%,respectively. The median overall survival was 22 months.Conclusion:Late-course intensity modulated radiotherapy appears to be a effective treatment for cervical and upper thoracic esophageal carcinoma,but local recurrence is still the main reason of treatment failure.关键词
食管肿瘤/调强适形放疗/疗效Key words
Esophageal carcinoma/Intensity modulated radiotherapy/Therapeutic effect引用本文复制引用
李广虎,马军,刘云琴,赵于飞,张红雁..33例颈及胸上段食管癌后程调强适形放疗疗效观察[J].中国医学创新,2012,(36):1-3,4,4.
