中国医学科学院学报2013,Vol.35Issue(3):332-336,5.DOI:10.3881/j.issn.1000-503X.2013.03.017
空肠置管肠内营养对胃癌患者术后生活质量的影响
Effect of Enteral Nutrition via Jejunostomy Catheter on Quality of Life in Gastric Cancer Patients Who Have Undergone Gastrectomy
摘要
Abstract
Objective To study the effect of enteral nutrition via jejunostomy catheter on the quality of life in gastric cancer patients who have undergone gastrectomy.Methods We retrospectively analyzed clinical data of 104 consecutive patients who had undergone curative resection for gastric cancer in Peking Union Medical College Hospital in 2011.All data were obtained from a prospectively maintained database of gastric cancer.The quality of life was compared between jejunostomy tube group (n =49) and tube-free group (n =55).Results The two groups were matched in gender,age,tumor size,tumor location,histological type,pTNM stage,type of surgery,body mass index (BMI),quality of life scales,and cycles of postoperative adjuvant chemotherapy (all P > 0.05).Also,the global health status (P =0.154),physical function score (P =0.321),role function score (P =0.492),and fatigue symptom score (P =0.845) were not significantly different between these two groups one month after surgery.Three and 6 months after the surgery,patients in the jejunostomy tube group had significantly higher overall health status scores (P < 0.001,P =0.038),physical function scores (P =0.004,P =0.005),and role function scores (P =0.002,P =0.038) and significantly lower fatigue symptom scores (P =0.020,P =0.043) when compared to patients from tube-free group.Conclusion Enteral nutrition via jejunostomy catheter can improve the quality of life of gastric cancer patients who have undergone gastrectomy.关键词
胃癌/胃切除术/空肠造口术/生活质量/肠内营养Key words
stomach neoplasms/gastrectomy/jejunostomy/quality of life/enteral nutrition分类
医药卫生引用本文复制引用
孟庆彬,于健春,康维明,马志强,叶欣,彭晶晶,曹战江,田树波..空肠置管肠内营养对胃癌患者术后生活质量的影响[J].中国医学科学院学报,2013,35(3):332-336,5.基金项目
北京协和医学院研究生创新基金(2011-1002-017)、北京自然科学基金(7132209)和中央保健专项基金(B2009A094)Supported by the Graduate Innovation Funding from Peking Union Medical College (2011-1002-017),Beijing Municipal Natural Science Foundation (7132209),and the Special Fund for Central Health (B2009A094) (2011-1002-017)