中国医学科学院学报2013,Vol.35Issue(3):357-361,5.DOI:10.3881/j.issn.1000-503X.2013.03.022
颈动脉内膜剥脱术围手术期生化标志物预警作用的研究进展
Advances in the Biochemical Markers of Complications Associated with Carotid Endarterectomy
吴立飞 1来志超 1刘昌伟 1李天佳 1刘暴1
作者信息
- 1. 中国医学科学院 北京协和医学院 北京协和医院血管外科,北京100032
- 折叠
摘要
Abstract
Carotid endarterectomy (CEA) has been proved to be an effective surgery to treat the cerebral ischemia caused by carotid atherosclerotic stenosis.However,there is still no effective mean for the early diagnosis of the CEArelated severe complications such as stroke and death.Many studies have explored the potential biomarkers for stroke alert,although there is still a long way to go for their actual application in clinical settings.The carotid atherosclerotic stenosis,the perioperative complications of CEA,and the stroke share similar pathogenic mechanisms,and some biomarkers such as S100B,matrix metalloproteinase 9,asymmetric dimethylarginine,and neuron-specific enolase have been studied in the clinical trails of CEA.This article summarizes recent advances in this field.关键词
卒中/颈动脉内膜剥脱术/生化标志物Key words
stroke/carotid endarterectomy/biomarker分类
医药卫生引用本文复制引用
吴立飞,来志超,刘昌伟,李天佳,刘暴..颈动脉内膜剥脱术围手术期生化标志物预警作用的研究进展[J].中国医学科学院学报,2013,35(3):357-361,5.