摘要
Abstract
Objective To explore the feasibility and safety of mixture solution of ropivacaine mesylate with sufentanil for brachial plexus nerve block anesthesia used in the upper extremity surgery.Methods 100 cases of elective upper extremity surgery with ASA Ⅰ-Ⅱ level were divided into the experimental group and control group by the random double-blind method.The experimental group (50 cases) was given 30 mL of the mixture solution A prepared by 0.894％ ropivacaine mesylate 15 mL plus sufentanil 10 μg (1 mL)plus 0.9％ sodium chloride injection 14 mL.The control group (50 cases) was given 30 mL of the mixture solution B prepared by 0.894％ ropivacaine mesylate 15 mL plus 0.9％ sodium chloride injection 15 mL.The vital signs,scores of analgesic,sedative and anesthetic effects after anesthesia were observed and compared between the two groups.Moreover,the changes of ECG,SPO2,MAP,HR,and other indicators after anesthesia were compared.Results The differences in MAP,HR,SPO2 at different timepoints between the two groups had no statistical significance (P＞0.05).The pain score at 10 min after anesthesia in the experimental group was significantly lower than that in the control group,anesthesia effect was faster.The sedative effect at 20 min after drug administration in the experimental group was obviously superior to that in the control group,the difference was statistically significant (P ＜ 0.05).In the anesthesia effect,the excellent and good rate was 96.00％ in the experimental group and 86.00％ in the control group with statistically significant differences between the two groups (P＜0.01).Two groups all did not appear adverse reactions during anesthesia.Conclusion In conducting brachial plexus nerve block anesthesia,the combination use of ropivacaine mesylate and sufentanil has fast onset time of analgesia,long analgesic time and good sedative effect than pure ropivacaine mesylate,can reduce sedative-hypnotic drug dosage and the occurrence rate of adverse reactions,which is a safe and effective method of nerve block.关键词
甲磺酸罗哌卡因/舒芬太尼/臂丛神经阻滞麻醉/上肢手术Key words
ropivacaine mesylate/sufentanil/brachial plexus nerve block anesthesia/upper extremity surgery分类
医药卫生
