摘要
Abstract
Objective To investigate the clinical efficacy of Lugua polypeptide combined with meloxicam in treatment of senile rheumatoid arthritis.Methods 68 elderly cases of rheumatoid arthritis were randomly divided into 2 groups (A and B) and treated with meloxicam and Lugua polypeptide combined with meloxicam,respectively.The erythrocyte sedimentation rate(ESR),C-reaction protein (CRP),rheumatoid factor(RF),liver function,blood routine and urine routine were detected before and after treatment in the two groups.The improvement conditions of joint pain,swelling and morning stiffness were observed.Results After 5 weeks treatment,the effective rates of the Lugua polypeptide combined with meloxicam group and the meloxicam group were 82.35％ and 70.59％,respectively; the morning stiffness time,average grip strength of two hands,joint tenderness number,joint swelling number rest pain,joint swelling index and joint tenderness index in the two groups were obviously improved with statistical differences(P ＜ 0.05).Among them,the improvement of the morning stiffness time,joint tenderness number and joint tenderness index in the Lugua polypeptide combined with meloxicam group was superior to that in the meloxicam group(P ＜ 0.05).Conclusion Lugua Polypeptide Injection combined with meloxicam has good effect and less adverse reactions in treatment of senile rheumatoid arthritis.关键词
鹿瓜多肽/美洛昔康/风湿性关节炎Key words
Lugua polypeptide/meloxicam/rheumatoid arthritis分类
医药卫生
