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青霉素V钾片处方工艺研究

冷崇姣 张太伦 徐洁

中国药业2013,Vol.22Issue(15):56-57,2.
中国药业2013,Vol.22Issue(15):56-57,2.

青霉素V钾片处方工艺研究

Prescription Technology Study on Penicillin V Potassium Tablets

冷崇姣 1张太伦 2徐洁2

作者信息

  • 1. 重庆市永川食品药品检验所,重庆 402160
  • 2. 西南药业有限公司,重庆 400038
  • 折叠

摘要

Abstract

Objective To solve the problem of related substances instability in Penicillin V Potassium Tablets.Methods The comparison of the dissolution curves between the optimized prescription by the orthogonal experiment and the control sample was performed,and then the changes of related substances and penicillin V potassium contents were investigated through accelerated test.Results The dissolving behavior and the stability of selfmade prescription was similar to the control sample.Conclusion Conducting the optimized design on the selfmade prescription by the orthogonal experiment,the studied new prescription is scientific and practical with good stability.

关键词

青霉素V钾/处方优化/正交试验/加速试验

Key words

Penicillin V potassium/optimized prescription/orthogonal experiment/accelerated test

分类

医药卫生

引用本文复制引用

冷崇姣,张太伦,徐洁..青霉素V钾片处方工艺研究[J].中国药业,2013,22(15):56-57,2.

中国药业

OACSTPCD

1006-4931

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