中国医药科学Issue(15):24-25,2.
尾加压素及其受体在大鼠肺缺血-再灌注损伤中的表达
Expression of urotensinⅡand its receptors during ischemia-reperfusion injury in rats in vivo
摘要
Abstract
Objective To investigate the expression of urotensin Ⅱ and its receptors during ischemia-reperfusion injury in rats. Methods Using IHC to observe the levels of UII and UT of rat pulmonary tissues and Using ELISA to observe the levels of U Ⅱ and UT of rat pulmonary tissues in different groups. Results U Ⅱ and UT was widely distributed in a variety of pulmonary cells.Its expression was boosted in pulmonary tissues and plasma after appearance of ischemia and reperfusion,especially in reperfusion stage,ischemia,reperfusion and up-regulation the expression of UT. Conclusion Ischemia and reperfusion can promote lung tissue cells to synthesize and excrete release U Ⅱ.关键词
尾加压素/受体/缺血-再灌注损伤/肺Key words
Urotensin Ⅱ/Receptors/Ischemia-reperfusion injury/Lung分类
医药卫生引用本文复制引用
马立民,饶旭光,段明科,杨伟,黎佩剑..尾加压素及其受体在大鼠肺缺血-再灌注损伤中的表达[J].中国医药科学,2012,(15):24-25,2.基金项目
广东省医学科研基金资助项目(A2008454) (A2008454)