中国中西医结合影像学杂志2013，Vol.11Issue(4)：350-353,4.DOI:10.3969/j.issn.1672-0512.2013.04.003
Alzheimer病乳头体MRI体积测量研究
MRI volume measurement of mammillary body in Alzheimer disease
骈文婷 1张敬 2杨明铭2
作者信息
- 1. 天津港口医院放射科,天津 300456
- 2. 天津医科大学总医院放射科,天津 300052
- 折叠
摘要
Abstract
Objective:To investigate the MB change in Alzheimer disease (AD) and evaluate its clinical application.Methods:The MR images of the normal adults,MCI and AD patients were downloaded from ADNI and there were 25 persons of each group.Measurement of MB volume repeated twice.Then the average volume was normalized.The methods included paired samples t test,independent samples t-test and single factor analysis of variance were used to analyze the MB volume indexes.Results:The compare inside each group of MCI or AD showed that the right MB was larger than the left and the differences were significant.Moreover,it showed no statistical difference of gender.The compare among the normal control,MCI and AD showed statistical differences.The MB volume change trend:normal control ＞ MCI＞ AD.Furthermore,side respective compare among three groups showed the same result.Conclusion:The atrophy of MB started in early AD and the progress is consistent.MB volume is a sensitive but poor specific index in early AD.Left MB atrophy is more apparent than right,which tipped on non symmetry of MB atrophy in AD.关键词
乳头体/阿尔茨海默病/磁共振成像Key words
Mammillary bodies / Alzheimer disease/ Magnetic resonance imaging分类
医药卫生引用本文复制引用
骈文婷,张敬,杨明铭..Alzheimer病乳头体MRI体积测量研究[J].中国中西医结合影像学杂志,2013,11(4):350-353,4.
