中外医学研究Issue(35)：3-4,5,3.
体外受精-胚胎移植中预处理对多囊卵巢综合征患者超排卵和结局影响的研究
The Study of Effects of Pretreatment on Controlled Ovarian Hyperstimulation and Outcomes of IVF-ET in Patients with PCOS
摘要
Abstract
Objective :To explore the effects of oral contraceptive pill (OCP) pretreatment in patients with polycystic ovarian syndrome (PCOS) undergoing controlled ovarian hyperstimulation (COS) for IVF-ET. Methods :112 patients with PCOS undergoing IVF-ET were randomized divided into group A (n=66), who received OCP pretreatment before cycle and group B (n=46),who did not received OCP.A retrospective analysis of the data of the patients was carried out for the assessment of the ovulation promoting effect of OCP pretreatment and the influence on the incidence of OHSS and IVF-ET results. Results :The formation of ovarian cyst was significantly decreased in group A (P<0.01).Compared with group B,the duration of gonadotropin stimulation and the gonadotropin consumption were both increased in group A (P<0.05).The ratio of ovum was increased in group A(91.87% versus 85.69%,P<0.05).But no significant differences were observed regarding on the proportion of patents who developed OHSS,the number of retrieved acolytes,fertilization rate,implantation rate and clinical pregnancy rate. Conclusion :OCP pretreatment in patients with PCOS could help the doctor to control the time of ovarian stimulation effectively.It may improve the synchronism of follicular development,though the duration of gonadotropin stimulation and the gonadotropin consumption were significantly increased in OCP pretreatment group. OCP pretreatment did not change the incidence of OHSS of medium degree or above.关键词
体外受精-胚胎移植/预处理/口服避孕药/多囊卵巢综合征Key words
IVF-ET/Pretreatment/Oral contraceptive pill/Polycystic ovarian syndrome分类
医药卫生引用本文复制引用
雷萍,吴重聪,阮永铭,蔡桂丰,王磊,杨桂艳..体外受精-胚胎移植中预处理对多囊卵巢综合征患者超排卵和结局影响的研究[J].中外医学研究,2012,(35):3-4,5,3.基金项目
珠海市科技计划基金资助项目(项目编号:2010B040102006) （项目编号:2010B040102006）
