北京生物医学工程2013,Vol.32Issue(4):375-379,5.DOI:10.3969/j.issn.1002-3208.2013.04.09.
鼻咽癌容积调强放射治疗剂量验证比较研究
Comparison of dose verification in volumetric modulated arc therapy for nasopharyngeal carcinoma
岳海振 1贾飞 1张健 1吴昊1
作者信息
- 1. 北京大学肿瘤医院暨北京市肿瘤防治研究所放疗科,恶性肿瘤发病机制及转化研究教育部重点实验室,北京100142
- 折叠
摘要
Abstract
Objective To compare the dose verification between 6X and 6X flattening filter-free(6FFF) in volumetric modulated arc therapy (VMAT) for the treatment of nasopharyngeal carcinoma(NPC),and verify the clinical feasibility of 6FFF VMAT plan.Methods The two dimensional ionization chamber matrix Array729 and OCTAVIUS Octagonal phantom from PTW Company were used to verify the 6X and 6FFF VMAT plan of 15 patients.Results Gamma 2D analysis criteria was used to evaluate the verification results (standard error as 3mm and 3%),the pass rate of local dose method for 6X was (95 ± 3) %,while the max dose method was (96 ± 3) %.For 6FFF,local dose method was (94 ± 3) %,and max dose method was (95 ± 3) %.Conclusions PTW Array729 can be used for clinical validation of 6X and 6FFF VMAT plans,the pass rate of 6FFF plan is lower than that of 6X plan,P > 0.05 for local dose,and P < 0.O1 for max dose.The pass rate of local dose method is less than max dose (P < 0.001) in the dose verification result for the same plan.关键词
鼻咽癌/容积调强放射治疗/剂量验证/非均整模式/Array729kKey words
nasopharyngeal carcinoma/ volumetric modulated arc therapy/ dose verification/flattening filter-free/ Array 729分类
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岳海振,贾飞,张健,吴昊..鼻咽癌容积调强放射治疗剂量验证比较研究[J].北京生物医学工程,2013,32(4):375-379,5.