波谱学杂志2013,Vol.30Issue(3):406-416,11.
美罗培南及其保护体的核磁共振波谱研究
NMR Spectral Analyses of Meropenem and Protected Meropenem
摘要
Abstract
Meropenem is a second-generation carbapenems antibiotics with an exceptionally broad spectrum of activity,which is currently used in the treatment of a variety of infections.In this paper,the 1H and 13C NMR chemical shifts of the compound in CDCl3 and CD3OD (solvents) were assigned.The assignment errors for C-6 and C-7 in the literature were corrected.The C-N bond rotational barrier of protected Meropenem was investigated.关键词
核磁共振(NMR)/旋转受阻/美罗培南/美罗培南保护体Key words
nuclear magnetic resonance (NMR)/ rotational barrier/ Meropenem/ protected Meropenem分类
数理科学引用本文复制引用
苏凤,梁现蕊..美罗培南及其保护体的核磁共振波谱研究[J].波谱学杂志,2013,30(3):406-416,11.基金项目
国家自然科学基金资助项目(21206148) (21206148)