重庆理工大学学报(自然科学版)2013,Vol.27Issue(8):62-65,4.DOI:10.3969/j.issn.1674-8425(z).2013.08.013
臭氧参与NAD+/NADH氧化还原反应机理的理论研究
Theoretical Discussion on Mechanism of the Reaction of Ozone and NAD +/NADH
摘要
Abstract
NAD +/NADH is a kind of necessary coenzyme in cellular energy metabolism,and it has been shown by numerous studies that cellular redox state especially NAD +/NADH level may be a primary control site in numerous biological process linked to rhythm,senescence,cancer and death.Ozone as a external factors can make the NADH stimulate response.Because of experimental conditions,the mechanism of the reaction of ozone and NAD +/NADH can be studied by theoretical chemistry.According to the literature research,overall reaction NADH + O3→ NAD + + HO · + O2 is the proton combined with electron transfer reaction,which has important significance to promote the dynamics of biological reaction using density functional theory on reaction mechanism research.关键词
NADH/臭氧/氧化还原反应Key words
NADH/ Ozone/ redox reaction分类
生物学引用本文复制引用
田文欣..臭氧参与NAD+/NADH氧化还原反应机理的理论研究[J].重庆理工大学学报(自然科学版),2013,27(8):62-65,4.