儿科药学杂志2013,Vol.19Issue(8):10-12,3.
米力农治疗小儿先天性心脏病并急性心力衰竭的疗效
Milrinone Therapy for Acute Heart Failure in Infants with Congenital Heart Disease
王祥 1黄希勇 1陈智 1肖云彬 1杨舟 1向金星1
作者信息
摘要
Abstract
Objective:To investigate the curative effect and safety of treatment for acute heart failure with congenital heart disease by milrinone.Methods:The patients of three months to two years of age (average eight months of age) who diagnosed congenital heart disease by ultrasonic cardiogram were enrolled and given conventional therapy.64 cases received milrinone additionally as the observation group,while 53 cases were as the control group.The improvement of heart function and the changes of ultrasonic cardiogram data after treatment were observed.Result:The effective rate of improvement of heart function in the observation group (64.1%) was higher than that in the control group (P<0.05).The ejection fraction,the left ventricular internal dimension of end-diastole (P<0.01),stroke volume,minute cardiac output,the left auricle inner diameter at end-diastole,and the percentage of shortened left ventricular stub (P < 0.05) in the observation group were improved.The improvements of the ejection fraction,the left ventricular internal dimension at end-diastole,and the left auricle inner diameter at end-diastole after treatment in the observation group were better than those in the control group (P<0.05).Conclusions:It is utility and safety for treatment of acute heart failure with congenital heart disease by low dose and temporary milrinone injection.关键词
米力农/先天性心脏病/心力衰竭Key words
Milrinone/ Congenital heart disease/ Heart failure分类
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王祥,黄希勇,陈智,肖云彬,杨舟,向金星..米力农治疗小儿先天性心脏病并急性心力衰竭的疗效[J].儿科药学杂志,2013,19(8):10-12,3.