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不同中药组方对高尿酸血症大鼠的影响

严群超 罗淑文 王帅帅

哈尔滨商业大学学报(自然科学版)2013,Vol.29Issue(4):394-397,4.
哈尔滨商业大学学报(自然科学版)2013,Vol.29Issue(4):394-397,4.

不同中药组方对高尿酸血症大鼠的影响

Effects of different traditional Chinese medicine prescription on hyperuricemic rats

严群超 1罗淑文 2王帅帅2

作者信息

  • 1. 暨南大学医学院,广州510632
  • 2. 广州蓝韵医药研究有限公司,广州510663
  • 折叠

摘要

Abstract

This paper observed the effects of different traditional Chinese medicine prescriptions on serum uric acid and the related metabolic index.Rats were divided into ten groups as follows:model group,control group,A,B,C,D sample groups (high-dose groups,low-dose groups).Rat models of hyperuricemic were established by oteracil potassium and had administration for thirty days.To make sure the model success and have a curative effect,the level of uric acid was determined after twenty seven days.The levels of GLU,CHOL,TG,UREA,CREA,UA and the kidney index was determined after thirty days.Compared with model group,the UA of all TCD sample groups were decreased significantly after twenty seven days.Furthermore,the UA of A,B,C groups (high-dose and low-dose groups) and the kidney index of A,B,C high-dose groups were decreased significantly at the day 30th,and the GLU,CHOL,TG,UREA,CREA levels of all groups had no significant difference.A,B,C groups could decrease the UA of hyperuricemic rats,they had a certain protective effect to the kidney for the first impression.

关键词

中药组方/高尿酸血症/血尿酸

Key words

traditional Chinese medicine prescriptions/ hyperuricemic/ serum uric acid

分类

医药卫生

引用本文复制引用

严群超,罗淑文,王帅帅..不同中药组方对高尿酸血症大鼠的影响[J].哈尔滨商业大学学报(自然科学版),2013,29(4):394-397,4.

哈尔滨商业大学学报(自然科学版)

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