江苏大学学报（医学版）2013，Vol.23Issue(4)：317-319,324,4.
急性冠脉综合征早期血清缺血修饰性白蛋白、高敏C反应蛋白及CXC趋化因子配体16水平检测的意义
Changes and clinical significance of ischemia modified albumin,high-sensitivity C-reactive protein and CXC ligand 16 in early acute coronary syndrome patients
顾志淼 1羊镇宇2
作者信息
- 1. 无锡市第八人民医院内科,江苏无锡214011
- 2. 南京医科大学附属无锡第一医院心内科,江苏无锡214023
- 折叠
摘要
Abstract
To explore the values of the serological screening for the ischemia modified albumin(IMA),high-sensitivity C-reactive protein(hs-CRP) and CXC ligand 16(CXCL16) in early acute coronary syndrome (ACS) patients.Methods:A total of 93 patients who were admitted to hospital in 3 hours after chest pain occurred were recruited and divided into control group (n =30) and acute coronary syndrome group(ACS n =63),IMA,hs-CRP and CXCL16 were detected by intravenous haemospasia and compared between the two groups.Results:The levels of serum IMA,hs-CRP and CXCL16 in ACS group were increased significantly compared with the control group (all P ＜ 0.01).The results of correlation analysis showed that IMA had a positive correlation with hs-CRP and CXCL16 (r =0.286,P ＜ 0.05 ;r =0.301,P ＜0.05).Conclusion:IMA,hs-CRP and CXCL16 were correlated with ACS,and CXCL16 was probably one of the responsible factors of the high serum IMA and hs-CRP levels.They could be the earliest sensitive indicators to the diagnosis and risk estimation of ACS.关键词
急性冠脉综合征/缺血修饰性白蛋白/高敏C反应蛋白/CXC趋化因子配体16Key words
acute coronary syndrome/ ischemia modified albumin/ high-sensitivity C-reactive protein/CXC ligand 16分类
医药卫生引用本文复制引用
顾志淼,羊镇宇..急性冠脉综合征早期血清缺血修饰性白蛋白、高敏C反应蛋白及CXC趋化因子配体16水平检测的意义[J].江苏大学学报（医学版）,2013,23(4):317-319,324,4.
