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反复自然流产患者外周血中白介素-8的表达

王振荣 刘娜 田喜凤 王丽 李宜学 郭全

实用临床医药杂志2013,Vol.17Issue(9):145-146,2.
实用临床医药杂志2013,Vol.17Issue(9):145-146,2.DOI:10.7619/jcmp.201309056

反复自然流产患者外周血中白介素-8的表达

Expression of IL-8 in the peripheral blood of patients with recurrent spontaneous abortion

王振荣 1刘娜 1田喜凤 2王丽 3李宜学 3郭全4

作者信息

  • 1. 河北省唐山市妇幼保健院,检验科,河北唐山,063000
  • 2. 河北联合大学,河北唐山,063000
  • 3. 河北省唐山市妇幼保健院,生殖遗传科,河北唐山,063000
  • 4. 河北省乐亭县医院检验科,河北乐亭,063600
  • 折叠

摘要

Abstract

Objective To study the expression and role of IL-8 in regulating immune system in patients with recurrent spontaneous abortions.Methods A total of 120 patients with recurrent spontaneous abortions were selected as study group.Another 120 normal women with early pregnancy who required abortions at the same period were selected as control group.ELISA was applied to measure IL-8 levels in peripheral plasma of the two groups.Results The IL-8 level was significantly higher in the study group (160.51 ± 11.30) pg/mL than in the control group (43.68 ± 8.31) pg/mL.The difference was statistically significant (P< 0.01).Conclusion The right amount of IL-8 would play an important role in maintaining normal pregnancy,and the increased the level of IL-8 may increase the risk of recurrent spontaneous abortion.

关键词

白介素-8/反复自然流产/外周血/表达

Key words

IL-8/recurrent spontaneous abortion/peripheral blood/expressions

分类

医药卫生

引用本文复制引用

王振荣,刘娜,田喜凤,王丽,李宜学,郭全..反复自然流产患者外周血中白介素-8的表达[J].实用临床医药杂志,2013,17(9):145-146,2.

实用临床医药杂志

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