实用临床医药杂志2013,Vol.17Issue(9):156-158,3.DOI:10.7619/jcmp.201309062
晚期上皮性卵巢癌腹膜后淋巴结清扫的临床价值
Clinical value of retroperitoneal lymph nodes dissection on advanced epithelial ovarian cancer
摘要
Abstract
Objective To evaluate the influence of retroperitoneal lymph nodes dissection (RPLND) on the prognosis of advanced epithelial ovarian cancer (EOC).Methods Sixty-seven patients with advanced EOC were randomly divided into research group (n =32) and control group (n=35).Patients in research group were treated with ovary cytoreductive surgery and standard postoperative chemotherapy,while those in the control group with ovary cytoreductive surgery,RPLND and standard postoperative chemotherapy.The operation time,intraoperative bleeding,postoperative morbidity as well as 1,3,and 5-year survival rates of the two groups were compared.Results The intraoperative bleeding,operation time and postoperative morbidity in research group were all less than those in the control group.There were no significant differences in 1,3,and 5-year survival rates of 2 groups whether residual cancer focus is less than 1.0 cm or more than it,whereas both 3 and 5-year survival rates of patients with postoperative residual cancer focus< 1.0 cm in the two groups were notably higher than those with residual cancer focus≥1.0 cm in the same group.Conclusion The ideal tumor reductive surgery is an important factor to influence the prognosis of patients with advanced EOC,whereas RPLND markedly increases the complications of advanced EOC in perioperative period instead of improving its survival rate.关键词
晚期上皮性卵巢癌/腹膜后淋巴结清扫/术后残留癌灶/生存率Key words
advanced epithelial ovarian cancer/retroperitoneal lymph nodes dissection/postoperative residual cancer focus/survival rate分类
医药卫生引用本文复制引用
许冬娣,汪艳..晚期上皮性卵巢癌腹膜后淋巴结清扫的临床价值[J].实用临床医药杂志,2013,17(9):156-158,3.基金项目
中国高校医学期刊临床专项资金(11320097) (11320097)