实用临床医药杂志2013，Vol.17Issue(15)：54-55,71,3.DOI:10.7619/jcmp.201315019
英夫利西单抗治疗强直性脊柱炎的临床疗效及安全性观察
Clinical effects and safety of infliximab in the treatment of ankylosing spondylitis
摘要
Abstract
Objective To investigate the clinical effects and safety of infliximab in the treatment of ankylosing spondylitis.Methods Sixty-eight patients with ankylosing spondylitis of our hospital were randomly divided into control group (n-33) and observation group (n =35).The control group was treated with traditional drugs,while the observation group with infliximab besides the traditional drugs.The clinical effects and adverse reactions between the two groups were compared.Results After treatment,the total efficacy rate of the observation group was 94.29 ％,remarkably higher than that of the control group.The duration of spinal morning stiffness,degree of pain,ESR and CRP in the observation group all obviously improved compared with those in the control group.Conclusion Infliximab has a very marked therapeutic effect in the treatment of ankylosing spondylitis,and is conducive to patients' recovery,so it is worthy of extensive promotion and application.关键词
英夫利昔单抗/强直性脊柱炎/临床疗效/安全性Key words
infliximab/ ankylosing spondylitis/ clinical effect/ safcty分类
医药卫生引用本文复制引用
赖爱云,蒋少泉,白茹..英夫利西单抗治疗强直性脊柱炎的临床疗效及安全性观察[J].实用临床医药杂志,2013,17(15):54-55,71,3.基金项目
中国高校医学期刊临床专项资金(11321079) （11321079）
