摘要
Abstract
Objective To evaluate the clinical effects of ambroxol in the treatment of the children with asthmatic bronchitis,and observe its effects on the serum inflammatory factors levels which are C reactive protein (CRP),tumor necrosis factor alpha (TNF-α) and interleukin 8 (IL-8).Methods One hundred and thirty-eight children with asthmatic bronchitis were selected and randomly divided into observation group and control group,69 in each group.The control group was treated with a regular therapy,while the observation group was treated with ambroxol hydrochloride injection adjuvant therapy in addition to the regular treatment mentioned above.The clinical curative effects of the two kinds of treatment were observed and the changes of serum CRP,TNF-α,IL-8 levels before and after the treatment were observed.Results After treatment,the curative ratio of the observation group was significantly higher than that of the control group (P ＜0.05).The serum CRP,TNF-α,IL-8 levels of patients in the two groups decreased significantly compared with those before treatment (P ＜ 0.05),and those in the observation group decreased more significantly than those in the control group (P ＜ 0.05).Conclusion When children with asthmatic bronchitis are treated with ambroxol on the basis of a regular treatment,an ideal outcome can be achieved and the inflammatory factors levels,such as CRP,TNF-α,IL-8,can be effectively improved.The method is worthy of the clinical application.关键词
喘息性支气管炎/氨溴索/C反应蛋白/肿瘤坏死因子-α/白细胞介素-8Key words
asthmatic bronchitis/ ambroxol/ C reactive protein/ tumor necrosis factor/interleukin 8/ clinical observation分类
医药卫生
